Japanese miRNA-eQTL Database

JAMIR-eQTL

You can search eQTLs by using any ID.

Explore JAMIR-eQTL

chromosome

chromosome

Browse and search all data using a chromosome region, chromosome:start postion-end postion

variant

Variant

Browse and search all data using a variant ID

miRNA

miRNA

Browse and search all data using a miRNA name or a miRBase accession

Dementia type + ALL
7
Serum donor
3,448
cis-miR-eQTL
2,487
trans-miR-eQTL
3,155,773

What are miR-eQTLs?

MicroRNAs (miRNAs) are approximately 22-nucleotide, small non-coding RNAs, which have been shown to regulate gene expression and cell development by binding to complementary regions of messenger transcripts. miRNA expression quantitative trait loci (miR-eQTL) analysis identifies genetic variants that affect miRNA expression: miRNA-genetic variant pairs. Identification of the genome-wide miR-eQTLs has proven to be a powerful and useful tool in the understanding of disease pathogenesis in human and other species.

miR-eQTLs are classified into two sub-groups: cis-miR-eQTLs and trans-miR-eQTLs. cis-miR-eQTLs refer to genetic variants that affect the expression of a local miRNA (i.e. the SNP is within 1 Mb from the miRNA transcript), while trans-eQTLs are genetic variants that affect the expression of a distant miRNA, often on different chromosomes.

describe miR-eQTL